Biosecurity
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Rose McDermott is a Professor of Political Science at Brown University.  She is currently a fellow at the Center for Advanced Studies in the Behavioral Sciences at Stanford University.  She holds a Ph.D. in Political Science and an M.A. in Experimental Social Psychology, both from Stanford University. She held a National Institute on Drug Abuse Post Doctoral Fellowship in Substance Abuse Treatment Outcome Research at the San Francisco VA through the University of San Francisco Psychiatry Department.  Professor McDermott has also held fellowships at the John M. Olin Institute for Strategic Studies and the Women and Public Policy Program, both at Harvard University. Professor McDermott's main area of research concerns political psychology in international relations. She is the author of Risk Taking in International Relations: Prospect Theory in American Foreign Policy (University of Michigan Press, 1998), Political Psychology in International Relations (University of Michigan Press, 2004), and Presidential Illness, Leadership and Decision Making (Cambridge University Press, 2007). She is co-editor of Measuring Identity: A Guide for Social Science Research, with Rawi Abdelal, Yoshiko Herrera, and Alastair Iain Johnson (Cambridge University Press, forthcoming).

She has written numerous articles and book chapters on experimentation, the impact of emotion on decision making, social identity, and evolutionary and neuroscientific models of political science.  She is currently involved in a series of projects investigating the endogenous sources of aggression, and a book project on pandemic disease.

Herbert Abrams is a professor of radiology, emeritus, at the Stanford School of Medicine and a member-in-residence at CISAC, where he directs the Project on Disabled Leadership. He was Professor and Director of Diagnostic Radiology at Stanford from 1960 to 1967, and was then appointed and served as Philip H. Cook Professor and Chairman of Radiology at Harvard University from 1967 to 1985. He returned to Stanford in 1985 as Professor of Radiology in order to spend most of his time in research in CISAC. Dr. Abrams' present focus is on presidential disability and its potential impact on decision making.

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Rose McDermott Visiting Fellow, Center for Advanced Study in the Behavioral Sciences, Stanford University; Professor of Political Science, University of California, Santa Barbara Speaker
Herbert Abrams Professor of Radiology, Emeritus and CISAC Member-in-Residence Commentator
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Abstract:  In 2003, General John Gordon, Assistant to the President for Homeland Security and former Deputy Director of the CIA asked his staff to do an end-to-end evaluation of U.S. biodefense posture.  As a result, Homeland Security Staff, directed by Dr. Kenneth Bernard, Special Assistant to the President, did a government-wide review of national preparedness and response to a bioterrorist attack.   The resulting assessment led in 2004 to the combined Homeland Security Presidential Directive #10 and National Security Presidetial Directive #17:  "Biodefense for the 21st Century."  Dr. Bernard will discuss the process and outcome of this policy that remains the U.S. national strategy for preventing and responding to a bioterrorist event. Accomplishments, outcomes and remaining gaps will be detailed, along with budget and policy implications for the next administration. 

Admiral Kenneth Bernard was appointed by President Bush to be Special Assistant to the President for Biodefense on the Homeland Security Council (HSC) in November 2002. Dr. Bernard chaired the Whitehouse Biodefense Policy Coordinating committee and drafted Decision Directives for President Bush on both "Biodefense for the 21st Century" and Agricultural Bioterrorism, and he was the White House point person on Project Bioshield - a $5.6 billion congressional bill that is speeding development and procurement of new countermeasures against biological, chemical and radiological terrorist threats.

In January 2001, Dr. Bernard was assigned by the U.S. Surgeon General to the office of Senator Bill Frist to work on international health issues of priority concern to both the Congress and the Department of Health and Human Services (HHS).   After September 11, however, he was called back to HHS to create the position of Special Adviser for National Security, Intelligence and Defense for the Department of Health and Human Services. From August 1998 to January 2001, he served on President Clinton's National Security Council (NSC) staff as Special Adviser to the Assistant to the President for National Security Affairs. Prior to joining the NSC, Dr. Bernard served as the International Health Attaché and senior representative of the U.S. Secretary of Health at the U.S. Mission to the UN in Geneva, Switzerland (1994-1998). From 1984-1989, he held positions as the Associate Director for Medical and Scientific Affairs in the Office of International Health, HHS, and as International Health Policy Adviser to the Director of the U.S. Peace Corps. He retired from the USPHS as a Rear Admiral.

He received his AB degree from the University of California, Berkeley in 1971, an M.D. from the University of California, Davis in 1975, and the DTM&H degree from the University of London School of Hygiene and Tropical Medicine in 1977.  He is a member of the Council on Foreign Relations.

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Dr. Kenneth Bernard former Special Assistant to the President for Biodefense, Homeland Security Council Speaker
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FSI senior fellow Stephen Stedman reviews John Bolton's book, Surrender Is not an Option, in the July/August issue of the Boston Review. "The memoir reads like an international relations primer done in the style of a modern morality tale," he writes. "Imagine Kenneth Waltz's classic Man, the State, and War as written by Ayn Rand."

One of the more remarkable underreported stories of 2008 was a speech in which the State department’s legal adviser John Bellinger admitted that there “are also realities about the International Criminal Court that the United States must accept.” He also stated that the Bush administration would work with the Court to maximize its chances of success in Darfur. Bellinger did not say that the United States might actually join the Court, but acknowledged that it enjoyed widespread international support and legitimacy, and that the United States could fruitfully cooperate with it on areas of mutual benefit.

Neither mea culpa nor volte-face, the speech nonetheless indicates the distance the administration has traveled in seven years. While Bellinger’s oratory went largely unnoticed by foreign policy wonks and the attentive public alike, it did not escape the scrutiny of John Bolton, who dismissed it as Clinton-era “pabulum” and reflective of “the yearning the Rice State Department has for acceptance” by academics and foreign intellectuals. He added ominously, “the fight resumes after Jan. 20.”

Bolton has been a powerful influence on Republican foreign policy for the last twenty years. Before his appointment as ambassador to the United Nations in 2005—which was achieved without Senate confirmation—Bolton dominated arms-control policy in the first Bush term. He killed the Anti-Ballistic Missile (ABM) Treaty, negotiations with North Korea, and the Biological Weapons Convention verification protocol. During the Clinton years, he campaigned tirelessly from his Heritage Foundation perch for missile defense and against global governance, which he seems to equate with global government. In 1998, when then-Secretary-General of the United Nations Kofi Annan released a report critical of both the United Nations secretariat and member states for the failure to prevent genocide in Srebrenica, Bolton chastized Annan for having the temerity to criticize governments for what they did or did not do in the former Yugoslavia. He added menacingly: “I think if he continues down this road, ultimately it means war, at least with the Republican Party.”

Bolton came of age politically during Barry Goldwater’s presidential campaign. The future policy heavyweight was a high schooler in Baltimore at the time. He honed his conservatism at Yale College and Yale Law School, ducked Vietnam through a National Guard posting (“looking back, I am not terribly proud of this calculation”), and got his first taste of Washington as an intern to Spiro Agnew. During the Bush Sr. presidency, Bolton was Assistant Secretary for International Organization Affairs in James Baker’s State Department, and was one of the first people who Baker called when he needed a posse of chad-disputing lawyers in Florida in November 2000. Bolton’s name keeps showing up in various articles about the fight inside the Republican Party for the soul of John McCain’s foreign policy.

All of this makes it imperative to read his memoirs, which clarify the stakes in the forthcoming election. Although it is hard to imagine Bolton in a McCain administration—his memoirs offend so many within his party, across the aisle, and overseas, that Bolton could not win Senate confirmation for capitol dog-catcher—Bolton will be plotting, pressing, and pushing to force McCain’s foreign policy back to the unilateralism of George Bush’s first term, when the war on terror meant never having to say you’re sorry. And there are important national security posts that do not require Senate approval.

The memoir reads like an international relations primer done in the style of a modern morality tale—imagine Kenneth Waltz's classic Man, the State, and War as written by Ayn Rand.

To Bolton, the United Nations is a “target rich environment,” and I had a front row seat to watch his gunslinging. In 2005 I served as Special Adviser to UN Secretary-General Kofi Annan. I was responsible for developing member-state support for his efforts to overhaul the United Nations. In that capacity, I was in Brussels in March 2005 when President Bush nominated Bolton as Ambassador to the United Nations. One high-ranking EU official recoiled in horror, and, to share his agita, repeated two of Bolton’s more famous lines: that “UN headquarters could lose ten floors and no one would know the difference,” and that “there was no United Nations.” How in the world, the official asked, could such a man be Ambassador to the United Nations?

Amidst nodding heads and shared pained looks, I offered that if I could pick the ten floors, I would agree with Bolton. Moreover, I said, any sentient being who spends time in Turtle Bay—the Manhattan site of the United Nations—will at some point in frustration say to themselves that there is no United Nations. Bolton’s sin was to say it publicly. Finally, I suggested that John Bolton was irrelevant: “If the President of the United States and the Secretary of State want a strong, effective United Nations, then Bolton will have to deliver. If they don’t, you could have John Kerry as the U.S. ambassador, and nothing will happen.”

Oh well; win some, lose some. Which is what Condoleeza Rice is rumored to have told a friend who asked how John Bolton could have possibly been nominated for the position under her watch.

Or more accurately, I was half right, half wrong. Reading this book, one can almost feel sorry for how unsuited Bolton was for his new job. For four years he had been the point man for breaking American commitments abroad, insulting allies and enemies alike, ditching the ABM Treaty, and unsigning the Rome Statute, which established the International Criminal Court (“my happiest moment at State”). In the heady days of the first Bush administration, when it believed the United States was so powerful it could get anything that it wanted without friends, partners, or institutions, Bolton was the “say no” guy, a job he performed with great brio. How could he know that in 2005 his big boss, the President, and his nominal boss, the Secretary of State, would actually decide that international cooperation was necessary, and that maybe we should start worrying about America’s free fall in world opinion? A pit bull in the first term, Bolton would be a yap dog in the second, grating on the Secretary of State, the President, and most American allies.

Almost sorry, for whatever else you say about John Bolton, he is not of the “we can disagree without being disagreeable” school of American politics. This is one of the nastiest, pettiest memoirs in the annals of American diplomatic history. Among the many targets of insults and catty remarks are former and present U.K. ambassadors to the United Nations Emyr Jones Parry, Adam Thomson (“I could never look at or listen to Thomson without immediately thinking of Harry [Potter] and all his little friends”), and John Sawers; recent U.K. foreign ministers; just about every UN civil servant mentioned; indeed, just about every U.S. civil servant mentioned, along with countless journalists and politicians.

The memoir reads like an international relations primer done in the style of a modern morality tale—imagine Kenneth Waltz’s classic Man, the State, and War as written by Ayn Rand. Bolton, usually singlehandedly, takes on what he calls the High Minded, the Normers (those who create international norms of behavior or try to “[whip] the United States into line with leftist views of the way the world should look”), the EAPeasers (career State Department officials who advocate negotiations with North Korea), the Risen Bureaucracy, the Crusaders of Compromise, the Arms Control True Believers, and the EUroids.

The book has the formulaic allegories typical of the genre—the young, innocent female (Kristen Silverberg, Assistant Secretary for International Organization Affairs) driven to tears after being berated by the cold-hearted career bureaucrat (Nicholas Burns); the noble knight (Bolton himself) fighting against the political higher ups who care only about “positioning themselves” (Rice) or their legacy (Colin Powell). And of course Bolton’s plaintive cries that the 2005-06 changes in administration policy occurred against the will of the President. One sees the peasants now: ‘If only the King knew what was happening, this would never go on.’

Now add a heaping dose of xenophobia. Foreigners, appeasing foreigners, foreigners claiming to know us better than we know ourselves: all loom large in Bolton’s memoirs. He insults the former Swedish foreign minister and President of the General Assembly Jan Eliasson as not only having “an ethereal Hammarskjöldian vision problem, but also a Gunnar Myrdal problem, yet another foreigner who ‘understood’ us better than we did ourselves.” (This is the Myrdal who shared the 1974 Nobel Prize in Economics with Friedrich Hayek, and whose classic book on race, An American Dilemma: The Negro Problem and Modern Democracy, was cited in Brown v. Board of Education.) At one point in his belittlement of a Bush political appointee, a special assistant to Condoleeza Rice, no less, Bolton adds that she was “a naturalized citizen originally from Pakistan,” in case we wondered why she could not possibly understand America’s real foreign policy interests. In Bolton’s worldview Zbigniew Brzezinski is probably a naturalized American citizen originally from Poland; Henry Kissinger, a naturalized American citizen originally from Germany.

In the Bolton universe, you want Iran and North Korea to be referred to the Security Council, so that when it fails to unite behind a resolute strategy, the United States is then free to take the tough action it needs to take. And in the case of North Korea, Bolton is clear about what that would be: “unilateralist, interventionist, and preemptive.” Is it any wonder that when it came to Iran and North Korea, our allies and adversaries were loathe to refer them anywhere near Bolton?

Richard Hofstadter’s 1964 article “The Paranoid Style in American Politics” was prompted by the supporters of the Goldwater campaign. Bolton strides right off the pages of Hofstadter’s essay:

He is always manning the barricades of civilization . . . he does not see social conflict as something to be mediated and compromised, in the manner of the working politician. Since what is at stake is always a conflict between absolute good and absolute evil, what is necessary is not compromise but the will to fight things out to a finish. Since the enemy is thought of as being totally evil and totally unappeasable, he must be totally eliminated—if not from the world, at least from the theatre of operations to which the paranoid directs his attention. This demand for total triumph leads to the formulation of hopelessly unrealistic goals, and since these goals are not even remotely attainable, failure constantly heightens the paranoid’s sense of frustration. Even partial success leaves him with the same feeling of powerlessness with which he began, and this in turn only strengthens his awareness of the vast and terrifying quality of the enemy he opposes.

According to Bolton, we do not need diplomats who negotiate, seek common ground, and strive for cooperative solutions. We need litigators who will go to the wall defending American interests, who will understand that when others say no, they mean no, and that therefore compromise is illusion. But in a world where the United States needs international cooperation for its own peace and prosperity, what comes next? Bolton’s answers are laughable—we stick with our “closest friends in the United Nations”—Israel, Palau and the Marshall Islands. Or we forge a new alliance with Japan, South Korea, Australia, Canada, and New Zealand to overcome the parasitic and paralytic EU. The road to global primacy runs through . . . Wellington?

There are, of course, some glaring contradictions in the memoirs. Bolton is known as a sovereignty hawk and he spells out the content of that doctrine as “greater independence and fewer unnecessary restraints.” The job of civil servants, politically appointed or career, is “to implement the president’s policies.” So it comes as a double shock when we find Bolton handing a draft Security Council resolution to the Israeli ambassador, in case the ambassador wants to ask his Prime Minister to appeal directly to Bush or Rice to change President Bush’s policy on Lebanon.

Another example concerns Bolton’s recurring beratement of UN officials for forgetting that they work for the member states. He then describes how one Under-Secretary-General, American appointee Christopher Burnham, surreptitiously showed him budget documents that put the United States at an advantage in budget negotiations. It is hard to see how you can have it both ways. Either UN officials serve all member states equally or the organization is up for grabs to the most powerful state.

But it is the big betrayal that is at the heart of the book. Facing a quagmire in Iraq, a faltering coalition in Afghanistan, a nuclear armed North Korea, the possibility of a nuclear Iran, and a war against terror that was creating more, not fewer, terrorists, Condoleeza Rice convinced President Bush that maybe they should stop digging a bigger hole for American foreign policy. And that meant actually trying diplomacy in North Korea, Iran, and the Middle East.

The losers were John Bolton and his acolytes; the winners were the professionals like Nicholas Burns and Christopher Hill. Faced with defeat and repudiation of the failed policies he advocated, Bolton’s response is familiar and tiresome: the professionals had secretly hijacked the president’s policy; the Secretary of State cares more about appeasing foreigners than protecting American interests.

The moment of reckoning for Bolton and for the President that nominated him is not described in the book, but it took place two months after Bolton left the administration. When the United States and North Korea reached a deal in February 2007 that holds the promise of denuclearizing the country, Bolton tried to scuttle it. Asked by reporters whether he was loyal to the President, Bolton answered, “I’m loyal to the original policy.”

What did Bolton achieve at the United Nations? Very little, which was fine by him and fine by the cast of nonaligned Ambassadors who oppose a more effective international organization. I asked one of them in December 2006 if he was happy that Bolton was leaving. He said, “No, we’ve learned how to deal with Mr. Bolton.” When I sought clarification, he said, “Look, Bolton comes in and asks for the sun, the moon, and the stars, and we say ‘no.’ He then says, ‘I told you so’ and leaves. Everybody is happy.”

Which returns us to the question of why anyone would want to wade through these 500 self-serving pages. The best answer: to remind yourself of the stakes of this upcoming election and why the United States needs more old-fashioned diplomacy and less paranoia and arrogance. A McCain presidency might not eschew diplomacy, but in the political free-for-all that is the Republican party, Bolton and his minions are always there, ready to denigrate any agreement or compromise, to sabotage and subvert real diplomacy.

Asked by reporters whether he was loyal to the President, Bolton answered, "I'm loyal to the original policy."

To understand the stakes, consider the little known and even less appreciated record of American negotiations with North Korea since 1994. Between what was called the “Agreed Framework” that brought North Korea back into the Nonproliferation Treaty (NPT) in 1994 and the end of 2000, the United States and North Korea reached twenty agreements on a wide array of issues. Certain of these agreements foundered in implementation, but an objective assessment shows that some of the noncompliance stemmed from constraints placed by American domestic politics.

The Bolton strategy killed the Agreed Framework, hoping through threats, sanctions, and use of force to end the North Korean regime. Unfortunately for Bolton—fortunately for the rest of us—our ally South Korea and our necessary partner China did not want to deal with the consequences: either a war or a collapsed, deadly state on their borders. In the end, they did not have to because North Korea left the NPT, developed a nuclear bomb, and tested it, bankrupting the Bolton policy and producing the sharp change of strategy that has born fruit in recent North Korean steps to end its nuclear program.

Writing about the successes of American negotiators in bringing North Korea and the United States back together in February 2007, former State Department negotiator Robert Carlin and Stanford Professor Emeritus John Lewis have described why Bolton and his crowd loathe diplomacy is loathed by Bolton and his crowd, and why it is so necessary:

Diplomats strive to put down words all of them can swallow and hopefully their superiors in [the] capital can stomach. Written agreements are difficult to reach. The pain often comes not so much in dealing with the other side but in dealing with your own. Unless you are dictating terms to a defeated enemy, you are going to have to compromise on something, probably several somethings, that will make many people unhappy. That was done for the February 13th agreement, and there is no shame to it.

John Bolton did much damage to American interests in the first Bush administration, but he was implementing the president’s policy. President Bush deserves the blame for putting Bolton in a position to continue hardming American interests even when the overall direction of policy changed.

Given that many countries treated the United States as radioactive in 2005; given that trust and confidence in the United States were at all time lows; given that our record was one of a violator of international law and human rights; President Bush, had he truly wanted to start to move the United States out of the hole he had been so assiduously digging, would have had to send to the United Nations an ambassador with extraordinary listening skills, who could work across various international chasms, rebuild respect for American diplomacy, and, yes, advocate agreements that would make a lot of people unhappy. Someone, in fact, a lot like our present Ambassador, Zalmay Khalilzad, a naturalized citizen originally from Afghanistan. Instead he sent . . . Yosemite Sam.

So back to January 20. A new American president will take office with grinding wars in Iraq and Afghanistan, a nuclear-armed North Korea, an Iran headed that way, and crises in Sudan, Israel and Palestine, Lebanon, and Pakistan. Our foreign policy is anathema; our reputation in tatters. Throw in big issues like global warming, non-proliferation, catastrophic terrorism, and a potential pandemic of a deadly new influenza. It is hard to see how any of these crises or issues can be solved without sustained international cooperation and strong international institutions. Take global warming: protecting Americans from its ravages will depend on exercising sovereignty to strike deals with other countries whose domestic behavior threatens us and whose security our domestic behavior threatens. A narrow view of sovereignty as the ability to do as we damned well please will be—quite literally—the death of us all.

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surrender is not an option
Surrender Is not an Option: Defending America at the United Nations and Abroad
by John Bolton. Threshold Editions, $27.00 (hardcover)

 

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Ever since the pioneering work of Philip Sartwell, the incubation period distribution for infectious diseases is most often modeled using a lognormal distribution. Theoretical models based on underlying disease mechanisms in the host are less well developed. This article modifies a theoretical model originally developed by Brookmeyer and others for the inhalational anthrax incubation period distribution in humans by using a more accurate distribution to represent the in vivo bacterial growth phase and by extending the model to represent the time from exposure to death, thereby allowing the model to be fit to nonhuman primate time-to-death data. The resulting incubation period distribution and the dose dependence of the median incubation period are in good agreement with human data from the 1979 accidental atmospheric anthrax release in Sverdlovsk, Russia, and limited nonhuman primate data. The median incubation period for the Sverdlovsk victims is 9.05 (95% confidence interval = 8.0-10.3) days, shorter than previous estimates, and it is predicted to drop to less than 2.5 days at doses above 106 spores. The incubation period distribution is important because the left tail determines the time at which clinical diagnosis or syndromic surveillance systems might first detect an anthrax outbreak based on early symptomatic cases, the entire distribution determines the efficacy of medical intervention—which is determined by the speed of the prophylaxis campaign relative to the incubation period—and the right tail of the distribution influences the recommended duration for antibiotic treatment.

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At an April 11 symposium in Washington, D.C., Homeland Security Secretary Michael Chertoff said while the best-laid plans are likely to change if a pandemic or bioterrorism attack hits the United States, having no plans in place is a sure guarantee for disaster. CISAC members Lynn Eden, Martha Crenshaw, and Mariano-Florentino Cuéllar participated in "Germ Warfare, Contagious Disease and the Constitution," a daylong event co-hosted by Stanford Law School. CISAC affiliate Laura K. Donohue conceived and developed the project, which aimed to bring together senior policy-makers and legal experts to discuss how issues of constitutional law inform responses to natural pandemics or bioterrorism attacks.

Secretary Michael Chertoff of the Department of Homeland Security delivered the keynote address April 11 at the panel titled “Germ Warfare, Contagious Disease and the Constitution” in Washington, D.C.

Although the best-laid plans are likely to change if a pandemic or bioterrorism attack hits the United States, having no plans in place is a sure guarantee for disaster, Homeland Security Secretary Michael Chertoff told policy-makers, government officials, constitutional law experts and law students at a symposium April 11 in Washington, D.C.

"Preparation won't eliminate the problems and the stress, and it is often said that no battle plan has ever survived first contact with the enemy," Chertoff told the roughly 200 people attending the event, "Germ Warfare, Contagious Disease and the Constitution," hosted by Stanford Law School and the Constitution Project, a nonprofit organization.

"But I can tell you this," Chertoff continued. "If you don't have a plan, you are definitely going to have the worst-case outcome. A plan at least gives you a running start."

During the symposium, experts discussed the need to reform the complex web of federal and state laws to enable agencies to respond effectively to deadly natural or manmade epidemics—from pandemic flu to smallpox and aerosolized anthrax—while protecting individual rights.

Earlier that day, about 60 people from the current and two previous presidential administrations, public health officials, Stanford academics and law students participated in a closed-door, fictitious scenario that explored the federal government's response to an unfolding deadly epidemic as it crossed state lines. Lynn Eden, associate director for research at Stanford's Center for International Security and Cooperation (CISAC) at the Freeman Spogli Institute for International Studies, moderated the session, which was developed in cooperation with experts from the Department of Homeland Security.

"I think it's the first time detailed issues of constitutional law have been brought to bear in a natural pandemic or bioterrorism exercise," Eden said afterward. "It's very hard to plan for a catastrophe. This approach brought another facet to bear on disaster planning."

Margaret Hamburg, a former assistant secretary in the Department of Health and Human Services, opened the symposium, which was broadcast live on C-SPAN from the Dirksen Senate Office Building. Kathleen Sullivan, director of the Stanford Constitutional Law Center, moderated a panel featuring Stanford law Professors Pamela Karlan and Robert Weisberg; Christopher Chyba, director of the Program on Science and Global Security at Princeton and a former CISAC co-director; Jeff Runge, assistant secretary in the Department of Homeland Security; Michael Greenberger, director of the Center for Health and Human Security at the University of Maryland; and Martin Cetron, director of the Division of Global Migration and Quarantine at the U.S. Centers for Disease Control and Prevention.

Sullivan opened the panel by reflecting on how recent health crises have informed ongoing legal and policy debates: "West Nile virus. Anthrax mailings. Avian flu—responses to these infectious disease issues and concern about bioterrorism are running about our minds as we think about the response to 9/11 and Hurricane Katrina, and the complex web of local, state and federal authority to deal with such emergencies. What does the Constitution have to say about our ability to deal with infectious disease, whether it's naturally occurring or composed as a weapon of violence?"

In the 21st century, Cetron explained, health officials still rely on a "14th-century toolbox of isolation and quarantine" to control an outbreak. That is "part of our modern reality," he said. "The biggest area is not lack of specific authority, but the fact that jurisdictions are highly complex when it comes to international ports of entry [and] interstate movement. There are often overlapping jurisdictions and overlapping authorities. If there's a gap in some of this, the risk is that neither the state nor the feds would want to step up to that responsibility."

Greenberger said state officials are often ignorant about what they can do in an emergency. "The powers given to governors are extraordinary," he said. Three statutes exist in Maryland to authorize declarations of emergency and allow the governor to enforce isolation and quarantine of infected people, order citizens to take treatment against their will, force doctors to serve in dangerous situations and seize hospitals. "What's extraordinary is that most governors don't even know they have this power," Greenberger said. "The extent of legal illiteracy in this area is shocking."

Despite such challenges, Chertoff praised the participants for tackling the issue. "I think for the first time we've begun to think very seriously and in a disciplined fashion about how to plan for dealing with a major natural pandemic or a major biological attack," he said. "I wish I could tell you these things are unthinkable. But the one thing I've learned in the last seven years is there's pretty much nothing that's unthinkable."

Stanford in Washington

Laura K. Donohue, a CISAC affiliate and a 2007 Stanford Law School graduate who is the inaugural fellow at the Stanford Constitutional Law Center, conceived the daylong event to bring together policy-makers and constitutional experts to discuss response to natural pandemics and bioterrorism. "It was a chance to bring together the policy world, both operational and strategic, and give them the opportunity to talk to legal experts," she said. "This helped policy-makers think through the issues and think outside the box, and it did so in a non-threatening manner."

Donohue said she was prompted to create the symposium after directing a CISAC-supported terrorism-response exercise in 2003 that involved more than 25 agencies at the national, state and local levels. "In these exercises involving first responders, legal issues always got pushed off the table," Donohue said. "I was struck by this. In an emergency, the law goes out the window. Then, when I got to law school, I saw the broader legal and constitutional context for this discussion."

With support from the directors at CISAC and Stanford Law School, and funding from donor Peter Bing and the Stanford Constitutional Law Center, Donohue brought the two groups together in a high-profile setting.

"This was Stanford in Washington," she said. "It was an opportunity for Stanford to be visible at the U.S. Senate with participation from leading people on these issues. There is no doubt we got an audience we wouldn't otherwise have attracted."

This article first appeared in Stanford Report, 4/16/2008.

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Arms races among invertebrates, intelligence gathering by the immune system and alarm calls by marmots are but a few of nature’s security strategies that have been tested and modified over billions of years. This provocative book applies lessons from nature to our own toughest security problems—from global terrorism to the rise of infectious disease to natural disasters. Written by a truly multidis­ciplinary group including paleobiologists, anthropologists, psychologists, ecologists, and national security experts, it considers how models and ideas from evolutionary biology can improve national security strategies ranging from risk assessment, security analysis, and public policy to long-term strategic goals.

Terence Taylor is the President and Director of the International Council for the Life Sciences and a former CISAC Science Fellow. He previously served with the United Nations as a Commissioner and Chief Inspector for Iraq on weapons of mass destruction and was a career officer in the British army. He also serves on the U.S. National Academy of Sciences Forum on Microbial Threats and is an adviser to the International Committee of the Red Cross. Mr. Taylor was also a member of the National Research Council Steering Committee on Genomic Databases for Bioterrorism Threat Agents and served as Chairman of the Permanent Monitoring Panel on Risk Analysis of the World Federation of Scientists.

Raphael Sagarin received his Ph.D. in marine ecology in 2001 from the University of California, Santa Barbara. Dr. Sagarin has served as a Geological Society of America congressional science advisor in the office of U.S. Representative Hilda L. Solis. Dr. Sagarin has used his insights as a biologist and policy advisor in his recent work on using biological insights to guide security planning and policy. Based on a short treatment of this topic in Foreign Policy, he organized a working group at the National Center for Ecological Analysis and Synthesis to explore a wide range of evolutionary insights into security analysis. Comprised of paleobiologists, psychologists, ecologists, anthropologists and security experts, the working group produced the forthcoming University of California Press volume: Natural Security: A Darwinian Approach to a Dangerous World, edited by Dr. Sagarin and Terence Taylor.

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Terence Taylor Director Speaker International Council for the Life Sciences
Raphael Sagarin Associate Director for Ocean and Coastal Policy, Nicholas Institute for Environmental Policy Solutions, Duke University Speaker
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The National Plant Diagnostic Network (NPDN) was created to enhance the capabilities of existing diagnostic laboratories in the nation to detect and report introduced pathogens, pests and weeds of high consequence to plant agriculture and natural ecosystems.  An important goal of the network is to coordinate diagnostic and scientific expertise at land-grant universities, state departments of agriculture, agencies within the USDA (CSREES and APHIS), and other organizations involved in agricultural production and security.  The program, which is administered through the USDA, was established in 2002 through funding created by the Homeland Security Act in response to concerns that agricultural pests and pathogens could be used as agents of bio-terrorism.  Responsibilities of the NPDN include the compilation and establishment of diagnostic protocols for priority agents, the development of a web-based distributed plant pest diagnostic and reporting system for the nation, the provision of up-to-date information on plant pests for the nation, the development of analytical tools to exploit these data, and the recruitment and training of first detectors.  The national network is organized into 5 regions, with regional centers located at the University of California, Davis (Western Region), Kansas State University (Great Plains Region), Michigan State University (North Central Region), the University of Florida (Southern Region), and Cornell University (Northeastern Region).  A parallel network for veterinary medicine, the National Animal Health Laboratory Network, also has been established with regional centers located at the same institutions as the NPDN regional centers.  The mission and design of the NPDN, its programs, and progress towards meeting network objectives, will be presented and discussed.

Richard Bostock is a professor and former chair (1999-2005) of the Department of Plant Pathology at the University of California, Davis.  In 2002, he was appointed as the founding Director of the Western Region of the National Plant Diagnostic Network (NPDN).  The NPDN is a distributed system comprised of public institutions for the purpose of quickly detecting and identifying high consequence pests and pathogens.  The network links plant health professionals, researchers and diagnostic labs throughout the region, providing a way for them to share information about occurrences of plant diseases and pests that could have an impact on the region's most economically important crops.   This information also is reported to first responders and decision makers. Funding for the network is provided through the United States Department of Agriculture. Dr. Bostock received his Ph.D. in Plant Pathology at the University of Kentucky in 1981, and was appointed to the faculty at UC Davis that year.  His research and teaching interests are the biochemistry and molecular biology of plant-microbe interactions and general plant pathology.  He teaches several courses in the department and in the Science and Society program on various aspects of plant pathology, plant-microbe interactions, and issues related to food production. 

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Richard Bostock Professor of Plant Pathology and Director, Western Plant Diagnostic Network Speaker University of California, Davis
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As we find ourselves at the start of the "biological century" with a wealth of potential benefits to public health, agriculture, and global economies, it is almost deliberately naive to think that the extraordinary growth in the life sciences might not be exploited for nefarious purposes. A report published in 2006 by an ad hoc committee of the National Academies of Science recognized that the breadth of biological threats is much broader than commonly appreciated and will continue to expand for the foreseeable future. The nature of these threats, and a set of potential approaches with which to mitigate these threats, will be reviewed.

David Relman, MD, is professor of medicine, and of microbiology and immunology at Stanford University. He is also chief, infectious diseases section, at the VA Palo Alto Health Care System in Palo Alto, California. His research is directed towards the characterization of the human indigenous microbial communities, with emphasis on understanding variation in diversity, succession, the effects of disturbance, and the role of these communities in health and disease.  This work brings together approaches from ecology, population biology, environmental microbiology, genomics and clinical medicine.  In addition, his research explores the classification structure of humans and non-human primates with systemic infectious diseases, based on patterns of genome-wide gene transcript abundance in blood and other tissues. The goals of this work are to recognize classes of pathogen and predict clinical outcome at early time points in the disease process, as well as to gain further insights into virulence. Past scientific achievements include the description of a novel approach for identifying previously-unknown pathogens, the identification of a number of new human microbial pathogens, including the agent of Whipple's disease, and some of the most extensive analyses to date of the human indigenous microbial ecosystem. See http://relman.stanford.edu

Among his other activities, Dr. Relman currently serves as Chair of the Board of Scientific Counselors of the National Institute of Dental and Craniofacial Research (NIH), Chair of the Institute of Medicine's Forum on Microbial Threats (U.S. National Academies of Science), member of the National Science Advisory Board for Biosecurity, and advises several U.S. Government departments and agencies on matters related to pathogen diversity, the future life sciences landscape, and the nature of present and future biological threats.  He co-chaired a three-year study at the National Academy of Sciences that produced a report entitled, "Globalization, Biosecurity, and the Future of the Life Sciences" (2006). He is a member of the American Academy of Microbiology. Dr. Relman received the Squibb Award of the IDSA in 2001, and was the recipient of both the NIH Director's Pioneer Award, and the Distinguished Clinical Scientist Award from the Doris Duke Charitable Foundation, in 2006.

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David Relman Professor of Medicine and of Microbiology and Immunology Speaker Stanford University
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David L. Heymann, assistant director-general for communicable diseases and the director general's representative for polio eradication at the World Health Organization (WHO), has joined CISAC as a consulting professor.

Heymann has dedicated much of his career as a medical doctor to investigating and fighting the spread of infectious diseases and mobilizing global efforts to prevent pandemics.

"Dr. Heymann's expertise on threats to health security is a welcome addition to CISAC," Siegfried Hecker, CISAC co-director, said. "He is deeply knowledgeable about the most severe disease-related threats as well as how best to build cooperative international efforts to reduce these threats."

Prior to assuming his current position at WHO, Heymann served as executive director of WHO's Communicable Diseases Cluster, which includes programs on infectious and tropical diseases. In that position, he oversaw the response to Severe Accute Respiratory Syndrome (SARS) in 2003.

Before joining WHO, Heymann worked for 13 years as a medical epidemiologist in sub-Saharan Africa, on assignment with the U.S. Centers for Disease Control. While there, he participated in investigating both the first outbreak of Ebola, in Yambuku (then Zaire) in 1976, and the second outbreak, in Tandala, in 1977. He directed the international response to the Ebola outbreak in Kikwit in 1995. Heymann also spent two years as a medical officer in the WHO smallpox eradication program in India prior to 1976.

Heymann spent two weeks in residence at Stanford last spring, co-hosted by CISAC and FSI, during which he delivered a a talk in FSI's Payne Lecture series. In the lecture, titled "Infectious Diseases across Borders: Public Health Security in the 21st Century," he discussed the collective responsibility to defend public health. He surveyed WHO's efforts to fight emerging and re-emerging infectious disease on every continent.

Among those efforts is a global network of scientists who monitor and collect viruses, sending samples to four WHO collaborating centers for analysis and tracking. This network detected the novel virus H5N1, known as avian flu, in 1997, a disease WHO continues to track closely.

Currently, Heymann said, the H5N1 virus is in the third of six phases in WHO's pandemic alert system, meaning that there have been cases of human infection but "no, or very infrequent, human-to-human spread."

Heymann emphasized, "It is important to prevent the disease at the source." At the same time, WHO is working to "provide universal access to vaccines," which, while not eliminating the disease, "will prevent sickness," he said.

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