Health and Medicine

FSI’s researchers assess health and medicine through the lenses of economics, nutrition and politics. They’re studying and influencing public health policies of local and national governments and the roles that corporations and nongovernmental organizations play in providing health care around the world. Scholars look at how governance affects citizens’ health, how children’s health care access affects the aging process and how to improve children’s health in Guatemala and rural China. They want to know what it will take for people to cook more safely and breathe more easily in developing countries.

FSI professors investigate how lifestyles affect health. What good does gardening do for older Americans? What are the benefits of eating organic food or growing genetically modified rice in China? They study cost-effectiveness by examining programs like those aimed at preventing the spread of tuberculosis in Russian prisons. Policies that impact obesity and undernutrition are examined; as are the public health implications of limiting salt in processed foods and the role of smoking among men who work in Chinese factories. FSI health research looks at sweeping domestic policies like the Affordable Care Act and the role of foreign aid in affecting the price of HIV drugs in Africa.

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About the talk: This presentation will discuss the centrality and challenges of health-specific technological progress in global health improvement. It will describe a research agenda and provide examples of specific empirical studies and findings that are part of the agenda.

About the speaker: Grant Miller is an Associate Professor of Medicine at the Stanford University School of Medicine, a Core Faculty Member at the Center for Health Policy/Primary Care and Outcomes Research, a Senior Fellow at the Freeman Spogli Institute for International Studies, and a Research Associate at the National Bureau of Economic Research (NBER). His primary interests are health economics, development economics, and economic demography.

Professor Miller’s primary focus is research and teaching aimed at developing more effective health improvement strategies for developing countries. His agenda addresses three major interrelated themes: (1) The major causes of population health improvement around the world and over time (2) Behavioral underpinnings of the major determinants of population health improvement - which factors have contributed most to population health gains, and why? (3) From insights to policy relevance: how can programs and policies use these behavioral insights to improve population health more effectively? 

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Grant Miller Associate Professor of Medicine; Senior Fellow, FSI Speaker
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CISAC Honors Student Mailyn Fidler has been awarded a Marshall Scholarship to continue her studies in international technology policy. She investigates security implications of the global trade in "zero-day" software exploits. Fidler has also worked as a consultant for Google Glass, autonomous vehicles and Internet access through atmospheric balloons, and was the co-founder and co-editor-in-chief of the Stanford Journal of Public Health.

Marshall Scholarships are named for former U.S. Secretary of State and U.S. Army General George Marshall, and are given to intellectually distinguished Americans to study in Britain.

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Abstract:

Nipah virus lives in large fruit bats in South and Southeast Asia. When people become infected with Nipah virus over half of them die. Nipah virus can also be transmitted from person to person. This talk will describe how this bat virus occasionally infects human populations and causes outbreaks through person-to-person transmission. It will explore the risk of a global pandemic of Nipah virus and consider appropriate policy responses.

Speaker bio:

Stephen Luby is Professor of Medicine in the Division of Infectious Diseases and Geographic Medicine; Deputy Director for Research at the Center for Global Health Innovation; Senior Fellow at the Woods Institute for the Environment and Senior Fellow at the Freeman Spogli Institute for International Studies at Stanford University.

Dr. Luby studied philosophy and earned a Bachelor of Arts summa cum laude from Creighton University. Dr. Luby earned his medical degree from the University of Texas Southwestern Medical School at Dallas and completed his residency in internal medicine at the University of Rochester-Strong Memorial Hospital. He studied epidemiology and preventive medicine at the Centers for Disease Control and Prevention.

Dr. Luby's former positions include leading the Epidemiology Unit of the Community Health Sciences Department at the Aga Khan University in Karachi, Pakistan for 5 years and working as a Medical Epidemiologist in the Foodborne and Diarrheal Diseases Branch of the Centers for Disease Control and Prevention exploring causes and prevention of diarrheal disease in settings where diarrhea is a leading cause of childhood death.  Immediately prior to his current appointment, Dr. Luby served for eight years at the International Centre for Diarrheal Diseases Research, Bangladesh (ICDDR,B), where he directed the Centre for Communicable Diseases. Dr. Luby was seconded from the US Centers for Disease Control and Prevention (CDC) and was the Country Director for CDC in Bangladesh.

Dr. Luby's research has focused on clarifying the burden of several communicable diseases in low income countries and developing and evaluating practical strategies to mitigate their impact. He is currently exploring circumstances where economic and political forces encourage environmental degradation that exerts substantial disease burden in low income countries, with a view to developing and evaluating interventions.

CISAC Central Conference Room

Stephen Luby Senior Fellow, Stanford Woods Institute for the Environment; Sr. Fellow, Freeman Spogli Inst. for International Studies; Research Deputy Director for the Stanford Univ. Center for Innovation in Global Health; Prof. of Medicine, Infectious Diseases Speaker
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Africa (Proceedings of the National Academy of Sciences 2013): USAID and the UN's World Food Program have proposed strategies for allocating ready-to-use (therapeutic and supplementary) foods to children in developing countries. Analysis is needed to investigate whether there are better alternatives. We use a longitudinal data set of 5657 children from Bwamanda to construct a statistical model that tracks each child's height and weight  throughout the first five years of life. We embed this model into an optimization framework that chooses which individual children should receive food based on a child's sex, age, height and weight, to minimize the mean number of disability-adjusted life years per child subject to a budget constraint. Our proposed policy compares favorably to those proposed by the aid groups. Time permitting, we will also discuss a recent analysis of a nutrition program in Guatemala that quantifies the age dependence in the impact of supplementary food, and develops a food allocation policy that exploits this age dependence and reduces child stunting.

India: Motivated by India's nationwide biometric program for social inclusion, we analyze verification (i.e., one-to-one matching) in the case where we possess 12 similarity scores (for 10 fingerprints and two irises) between a resident's biometric images at enrollment and his biometric images during his first verification. At subsequent verifications, we allow individualized strategies based on these 12 scores: we acquire a subset of the 12 images, get new scores for this subset that quantify the similarity to the corresponding enrollment images, and use the likelihood ratio to decide whether a resident is genuine or an imposter. Compared to the policy currently used in India, our proposed policy provides a five-log (i.e., 100,000-fold) reduction in the false reject rate while only increasing the mean delay from 31 to 38 seconds.

A full speaker bio is available on CISAC's website. 

CISAC Conference Room

Graduate School of Business
Stanford University
Stanford, CA 94305-5015

(650) 724-1676 (650) 725-0468
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Jeffrey S. Skoll Professor of Management Science
CISAC Affiliated Faculty Member
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Lawrence Wein is the Jeffrey S. Skoll Professor of Management Science at the Graduate School of Business, Stanford University, and an affiliated faculty member at CISAC. After getting a PhD in Operations Research from Stanford University in 1988, he spent 14 years at the Sloan School of Management at MIT, where he was the DEC Leaders for Manufacturing Professor of Management Science. His research interests include mathematical models in operations management, medicine and biology.

Since 2001, he has analyzed a variety of homeland security problems. His homeland security work includes four papers in Proceedings of the National Academy of Sciences, on an emergency response to a smallpox attack, an emergency response to an anthrax attack, a biometric analysis of the US-VISIT Program, and an analysis of a bioterror attack on the milk supply. He has also published the Washington Post op-ed "Unready for Anthrax" (2003) and the New York Times op-ed "Got Toxic Milk?", and has written papers on port security, indoor remediation after an anthrax attack, and the detention and removal of illegal aliens.

For his homeland security research, Wein has received several awards from the International Federation of Operations Research and Management Science (INFORMS), including the Koopman Prize for the best paper in military operations research, the INFORMS Expository Writing Award, the INFORMS President’s Award for contributions to society, the Philip McCord Morse Lectureship, the Frederick W. Lanchester Prize for best research publication, and the George E. Kimball Medal. He was Editor-in-Chief of Operations Research from 2000 to 2005, and was elected to the National Academy of Engineering in 2009.   

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Lawrence Wein Jeffrey S. Skoll Professor of Management Science; CISAC Affiliated Faculty Member Speaker
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CISAC co-director David Relman, the Thomas C. and Joan M. Merigan Professor and professor of microbiology and immunology and chief of infectious diseases at the VA-Palo Alto, and Susan Holmes, the John Henry Samter University Fellow in Undergraduate Education and professor of statistics, will share a $6.2 million federal grant to examine the effects of perturbations in humans' microbial ecology.

They are among eight Stanford scientists to receive the Transformative Research Awards from the National Institutes of Health.

Relman and Holmes will monitor the microbial ecosystems of healthy humans before, during and after several types of planned disturbance, such as changes in diet or antibiotic administration. They will apply novel mathematical methods to the data generated from these clinical experiments and identify features associated with future stability or recovery from these disturbances, with the goal of predicting disease and restoring health.

 

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David Relman
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More information TBA. 

 

Speaker bio:

David A. Relman, M.D., is the Thomas C. and Joan M. Merigan Professor in the Departments of Medicine, and of Microbiology and Immunology at Stanford University, and chief of infectious diseases at the Veterans Affairs Palo Alto Health Care System in Palo Alto, California. He is also co-director of the Center for International Security and Cooperation and senior fellow at the Freeman Spogli Institute for International Studies at Stanford University.

Dr. Relman’s primary research focus is the human indigenous microbiota (microbiome), and in particular, the nature and mechanisms of variation in patterns of microbial diversity and function within the human body, and the basis of microbial community resilience. His work was some of the first to employ modern molecular methods in the study of the microbiome, and provided the first in-depth sequence-based analyses of microbial community structure in humans. During the past few decades, his research has included pathogen discovery and the development of new strategies for identifying previously-unrecognized microbial agents of disease. A resulting publication was cited by the American Society for Microbiology as one of the 50 most important papers in microbiology of the twentieth century. He has also served as an advisor to a number of agencies and departments within the U.S. Government on matters pertaining to host-microbe interactions, emerging infectious diseases, and biosecurity. He co-chaired a widely-cited 2006 study by the National Academies of Sciences (NAS) on “Globalization, Biosecurity, and the Future of the Life Sciences”, and served as vice-chair of a 2011 National Academies study of the science underlying the FBI investigation of the 2001 anthrax mailings. He currently serves as a member of the National Science Advisory Board for Biosecurity (2005-), a member of the Committee on Science, Technology, and Law at the National Academy of Science (2012-15), a member of the Science, Technology & Engineering Advisory Panel for Lawrence Livermore National Laboratory (2012-), as Chair of the Forum on Microbial Threats at the Institute of Medicine (NAS) (2007-), and as President of the Infectious Diseases Society of America (2012-2013).

Dr. Relman received an S.B. (Biology) from MIT (1977), M.D. (magna cum laude) from Harvard Medical School (1982), completed his clinical training in internal medicine and infectious diseases at Massachusetts General Hospital, served as a postdoctoral fellow in microbiology at Stanford University, and joined the faculty at Stanford in 1994. He received an NIH Director’s Pioneer Award in 2006, was elected a Fellow of the American Academy of Microbiology in 2003 and the American Association for Advancement of Science in 2010, and was elected a Member of the Institute of Medicine in 2011.

 

 

Reuben W. Hills Conference Room

CISAC
Stanford University
Encina Hall, E209
Stanford, CA 94305-6165

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Senior Fellow at the Freeman Spogli Institute for International Studies
Thomas C. and Joan M. Merigan Professor
Professor of Medicine
Professor of Microbiology and Immunology
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David A. Relman, M.D., is the Thomas C. and Joan M. Merigan Professor in the Departments of Medicine, and of Microbiology and Immunology at Stanford University, and Chief of Infectious Diseases at the Veterans Affairs Palo Alto Health Care System in Palo Alto, California. He is also Senior Fellow at the Freeman Spogli Institute for International Studies (FSI) at Stanford, and served as science co-director at the Center for International Security and Cooperation at Stanford from 2013-2017. He is currently director of a new Biosecurity Initiative at FSI.

Relman was an early pioneer in the modern study of the human indigenous microbiota. Most recently, his work has focused on human microbial community assembly, and community stability and resilience in the face of disturbance. Ecological theory and predictions are tested in clinical studies with multiple approaches for characterizing the human microbiome. Previous work included the development of molecular methods for identifying novel microbial pathogens, and the subsequent identification of several historically important microbial disease agents. One of his papers was selected as “one of the 50 most important publications of the past century” by the American Society for Microbiology.

Dr. Relman received an S.B. (Biology) from MIT, M.D. from Harvard Medical School, and joined the faculty at Stanford in 1994. He served as vice-chair of the NAS Committee that reviewed the science performed as part of the FBI investigation of the 2001 Anthrax Letters, as a member of the National Science Advisory Board on Biosecurity, and as President of the Infectious Diseases Society of America. He is currently a member of the Intelligence Community Studies Board and the Committee on Science, Technology and the Law, both at the National Academies of Science. He has received an NIH Pioneer Award, an NIH Transformative Research Award, and was elected a member of the National Academy of Medicine in 2011.

Stanford Health Policy Affiliate
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David Relman Thomas C. and Joan M. Merigan Professor, Departments of Medicine and of Microbiology and Immunology, Stanford School of Medicine; CISAC Co-Director; FSI Senior Fellow; Stanford Health Policy Affiliate Speaker
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CISAC's Drew Endy has been honored at the White House as a "Champion of Change." The award is given to experts and researchers who promote the use of open scientific data and publications for the benefit of humanity. Endy was recognized for his trailblazing work as an advocate of public domain biotechnology.
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Symposium description:

A unique, two-day symposium at which an international panel of leading medical and biological scientists, nuclear engineers, and policy experts will make presentations on and discuss the bio-medical and ecological consequences of the Fukushima disaster, will be held at The New York Academy of Medicine on March 11-12, 2013, the second anniversary of the accident.

A project of The Helen Caldicott Foundation, the symposium is being co-sponsored by Physicians for Social Responsibility.

View the video online at The Helen Caldicott Foundation.

Herbert Abrams Professor of Radiology, Emeritus; CISAC Faculty Member Speaker
Panel Discussions
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