The siting and construction of high-level biocontainment facilities involves a complex review process with environmental impact documents, legally mandated reviews, and public involvement in decision making about associated risks. In some cases, serious public opposition and legal challenges may arise during the review and approval stages of a project. The recent proposed construction of NIH-NIAID regional and national biocontainment labs provided an opportunity for a real-time study of the review and approval processes associated with labs in many different locations. By analyzing environmental impact documents, mass media coverage, internet communications, and detailed timelines at the various labs, it was possible to identify common issues and features associated with labs in general, as well as specific concerns associated with those where public controversies and opposition arose. The study focused on both good and bad experiences at various recently proposed lab sites and compared them with other past case examples to identify 'lessons learned' that are relevant to both current and future biocontainment projects. Overall, the study documented the continuing importance of trust, transparency, and due process in public decision making and highlighted the importance of developing and implementing a comprehensive pro-active risk communication strategy at the earliest stages of project planning. The study also documented indications of public insecurity associated with biodefense research, which may translate into future problems for public health researchers.

Margaret Race is an ecologist working with NASA through the SETI Institute in Mountain View, Calif. She recently completed a study on public decision making and risk communication associated with the construction of BSL-3 and BSL-4 biocontainment labs nationwide. The study, which was begun during a fellowship at Stanford University and CISAC, reflects her longstanding interest in risk perceptions, legal and societal issues, public communication and education associated with controversial science and technological proposals. In her work with NASA, she focuses on planetary protection and the search for extraterrestrial life--which will someday involve construction of a BSL-4 biocontainment lab for handling and testing scientific samples returned from Mars and other solar system locaitons. During the past decade, she has been a lead member of an international team of researchers that helped NASA develop a protocol for the quarantine, handling, and testing of extraterrestrial samples from Mars. She has served on numerous National Resource Council studies analyzing risk communication and societal issues associated environmental protection on Earth and in space. Dr. Race received her BA degree in Biology and MS degree in Energy Management and Policy from the University of Pennsylvania, and her Ph.D. in Ecology/Zoology from the University of California at Berkeley. Her teaching and research work has included positions at Stanford University (Human Biology Program), UC Berkeley (Assistant Dean, College of Natural Resources), and Office of the President, University of California (Senior Science Policy Analyst and Director of Planning). She was also a Postdoctoral Fellow in Marine Policy and Ocean Management at Woods Hole Oceanographic Institution.

After considering trends in the role of nuclear weapons and some lessons from history, this presentation examines nuclear signaling in the context of the evolving role of nuclear weapons (for deterrence and dissuasion, among other purposes) and likely developments of U.S. nuclear forces and their concepts of operation for regional crises. Following the development of a 2015 regional crisis scenario, the utility of potential signaling options are examined in light of current U.S. nuclear force development trends. Options for future U.S. nuclear force and concepts development for signaling as part of overall tailored deterrence are identified and examined.

Owen Price is a consulting visiting fellow in the Center for Strategic and International Studies International Security Program, on sabbatical until March 2007 from the U.K. Atomic Weapons Establishment (AWE), where he has worked for 12 years. Most recently, he led a team of systems engineers working on AWE capability programs, work designed to ensure that AWE continues to be able to design and field new warheads of tasked to do so by the British government. From 2000 to 2003, he led the AWE Verification Research Program, was a technical adviser to the British Foreign and Commonwealth Office, and was a member of the U.K. delegation to the Non-Proliferation Treaty Preparatory Committee Meetings in 2003 and 2004. Price holds an MA in engineering from the University of Cambridge, England, and an MBA in engineering management from the University of Bradford, England. He is currently reading (part time) for an MSc in systems engineering at the U.K. Defense Academy, Cranfield University, Shrivenham, England. He is a member of the International Institute for Strategic Studies and is a British national.

Satellites are absolutely essential and extremely vulnerable for national and economic security. How do we deal with this dilemma?

Michael Krepon is co-founder of the Henry L. Stimson Center and the author or editor of eleven books and over 350 articles. Prior to co-founding the Stimson Center, Krepon worked at the Carnegie Endowment for International Peace, the U.S. Arms Control and Disarmament Agency during the Carter administration, and in the U.S. House of Representatives, assisting Congressman Norm Dicks. He receive an MA from the School for Advanced International Studies, Johns Hopkins University, and a BA from Franklin & Marshall College. He also studied Arabic at the American University in Cairo, Egypt.

Krepon divides his time between Stimson's South Asia and space security projects. The South Asia project concentrates on escalation control, nuclear risk reduction, confidence building, and peace making between India and Pakistan. This project entails field work, publications, and Washington-based programming, including a visiting fellowship program. The space security project seeks to promote a code of conduct for responsible space-faring nations and works toward stronger international norms for the peaceful uses of outer space.

Bioterrorism is a growing threat. While the U.S. government has spent considerable sums on programs designed to protect the United States from a biological attack, no clear strategy has been articulated to guide planning and expenditures. This talk will present the outlines of a coherent strategy for coping with bioterrorism that includes diplomacy, deterrence and defense, with the emphasis on defense.

Dean Wilkening directs the Science Program at CISAC. He holds a Ph.D. in physics from Harvard University and spent 13 years at the RAND Corporation prior to coming to Stanford in 1996. His major research interests have been nuclear strategy and policy, arms control, the proliferation of nuclear, biological, and chemical weapons, ballistic missile defense, and conventional force modernization. His most recent research focuses on ballistic missile defense and biological terrorism. His work on missile defense focuses on the broad strategic and political implications of deploying national and theater missile defenses, in particular, the impact of theater missile defense in Northeast Asia, and the technical feasibility of boost-phase interceptors for national and theater missile defense. His work on biological weapons focuses on understanding the scientific and technical uncertainties associated with predicting the outcome of hypothetical airborne biological weapon attacks, with the aim of devising more effective civil defenses, and a reanalysis of the accidental anthrax release in 1979 from a Russian military compound in Sverdlovsk with the aim of improving our understanding of the human effects of inhalation anthrax.

Emily Harris is a Knight Fellow at Stanford University this year. She was born in Philadelphia, Pennsylvania and earned a bachelor's degree in Russian and East European studies at Yale University. She got her first journalism job as a morning news director at KBOO, a community radio station in Portland, Oregon in 1993. Harris worked from Moscow as a freelance writer and radio and TV reporter in the mid-nineties before moving to Los Angeles, where she was the senior producer of a daily radio talk show at KCRW. She returned to reporting as a correspondent specializing in business and economics for a number of TV and radio programs around the globe before being hired by National Public Radio in Washington, D.C. in 2000. She worked as a general assignment reporter in Washington for NPR, then joined NOW with Bill Moyers on PBS. In late 2002 she was named NPR's Berlin correspondent, a post from which she has covered Central and Eastern Europe as well as spent considerable time in Iraq. She was a key member of the NPR team that won a Peabody for coverage of Iraq in 2004.

On May 5, 2006, Brazil officially inaugurated a plant that will produce enriched uranium to supply the country's two nuclear power reactors. Brazilian officials have claimed that providing domestic enrichment services will account for savings to the national nuclear industry. This work is a preliminary evaluation of the economic relevance of the Brazilian enrichment program, taking into account cost of production and the market price for uranium enrichment.

Belkis Cabrera-Palmer is a science fellow at the Center for International Security and Cooperation, Stanford University. She received her Ph.D. in Physics form Syracuse University in May 2005. Her research interest comprises the study of energy resources in Latin America, and this year she has focused on the role of nuclear power in electricity generation in Brazil. Her current research project is entitled "On the Uranium Enrichment Program in Brazil", and aims to evaluate the economic relevance a national enrichment program has in Brazil's nuclear industry.

Nearly all male adults illegally crossing the US-Mexico border, most of whom are Mexicans, are seeking employment, although a few may be terrorists. We are particularly interested in the impact of immigration strategies on the probability for an OTM (Other than Mexican) terrorist to enter the country, which is based on four models: (a) Discrete Choice Model, (b) Border Apprehension Model, (c) DRO (Detention and Removal Operations) Model, and (d) Illegal Wage Model.

These four models explain the inter-relationship among four key variables -- crossing rate, apprehension probability, removal probability, and illegal wage, which are also affected by other factors, such as detention policy, DRO beds, work site enforcement and legalization policy.

Model (a) introduces a combination of the multinomial-logit model with backward recurrence; model (b) is mainly based on the data we have and the previous research work; model (c) is a 2-class priority queueing analysis with inhomogeneous incoming rate; and model (d) includes some economic theory. Numerical results and discussions are given based on the model parameters existing or estimated from the data provided.

Yifan Liu is currently a CISAC science fellow, and Ph.D. student in the Institute for Computational and Mathematical Engineering at Stanford University. His Ph.D. dissertation, under the supervision of Lawrence Wein at the Graduate school of Business, uses operation research methods to construct mathematical models for homeland security issues, and solve these models both analytically and numerically.

Professor Li Shian is a Professor of History and Director of American and European Studies at Beijing's Renmin University. He is the Chief Editor of the journal World History and is a Council Member of the China Society for Human Rights Studies, which he has represented at several international human rights conferences. A former Chairman of the History Department at Renmin University, Dr. Li was awarded his doctorate at the University of Birmingham in 1989, and did post-graduate work at Stanford University from July 1990 to October 1992. He is the author of several books, including A Study of American Human Rights History and A History of the Development of Western Capitalism.

Professor Li will deliver remarks on the role human rights plays in US-China relations, from a Chinese perspective. He will begin with an exposition of human rights in traditional and post-1949 China, and drawing on this, review US-China exchanges on human rights post-June 4, 1989. He will discuss different approaches for addressing what Chinese and Americans both recognize as a central if contentious issue in their relations: respect for international laws as they protect both individual and collective freedoms.