Bioterrorism
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Abstract: The threat of biological attack on the people of the United States and the world, whether intentional, natural or accidental, is of growing concern, both in spite of and because of significant technological advances over the past four decades. As a global leader, the United States needs a comprehensive policy approach for managing future attacks, which incorporates technologic elements from rapid detection through appropriate response. American and international responses to recent infectious disease outbreaks such as anthrax (intentional, accidental), H5N1 influenza (natural) and ebola (natural) have managed to contain these events ‐ with the paradoxical effect on policy makers, both political and administrative, of relief (“missed that bullet”, “we must be doing this right”), rather than serving as wake‐up calls. A challenge in merging technological solutions into policy lies in the rapid advances across the multiple sciences. Translation of these ongoing technologic advances for policy leaders is an essential element in effective policy development. Incorporation of technologic solutions into biosecurity policy construction, combined with motivated leadership, has the potential for enhancing future national and global responses to unprecedented biological attacks.

About the Speaker: Patrick J. Scannon, M.D., Ph.D. is XOMA's Company Founder, Executive Vice President, Chief Scientific Officer and a member of its Board of Directors. Since 1980, Dr. Scannon has directed the Company's product identification, evaluation and clinical testing programs for novel therapeutic monoclonal antibodies and proteins against infectious, oncologic, metabolic and immunologic diseases. As Chief Scientific Officer, he leads evaluations for new therapeutic antibody identification and discovery programs. 

Dr. Scannon holds a Ph.D. in organic chemistry from the University of California, Berkeley and an M.D. from the Medical College of Georgia. He completed his medical internship and residency in internal medicine at the Letterman Army Medical Center in San Francisco. A board-certified internist, Dr. Scannon is also a member of the American College of Physicians. He is the inventor or co-inventor of several issued U.S. patents, and has published numerous scientific abstracts and papers.

Dr. Scannon has served as a member of the Research Committee for Infectious Diseases Society of America (IDSA), the National Biodefense Science Board (NBSB, a federal advisory board for the Department of Health and Human Services), the chair of the Chem/Bio Warfare Defense Panel for the Defense Threat Reduction Agency (DTRA) and a member of the Defense Sciences Research Council (DSRC, a research board for Defense Advanced Research Projects Agency (DARPA)). He has served as a Trustee of the University of California Berkeley Foundation and as a member of the University of California Berkeley Chancellor's Community Advisory Board. Dr. Scannon is currently on the Board of Directors of Pain Therapeutics, Inc.

Technology Impact on Biosecurity Policy and Practice
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Patrick J. Scannon Founder, Executive Vice President, Chief Scientific Officer XOMA
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Abstract

The U.S. government is surreptitiously collecting the DNA of world leaders, and is reportedly protecting that of Barack Obama. Decoded, these genetic blueprints could provide compromising information. In the not-too-distant future, they may provide something more as well—the basis for the creation of personalized bioweapons that could take down a president and leave no trace.

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Atlantic Magazine
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The book The Soviet Biological Weapons Program: A History by Milton Leitenberg and Raymond A. Zilinskas is scheduled to be published on May 14, 2012 by Harvard University Press. This book describes and analyzes in detail the Soviet biological warfare (BW) program, from its inception in 1928 to likely termination in 1992. The two most vexing questions that the authors attempt to answer are; in the final analysis, what were the Soviet BW program’s accomplishments? Second, might Soviet accomplishments related to enhancing biological weaponry be made available to future national or terrorist BW programs? This presentation will explain why these questions are difficult to answer but nevertheless will propose answers to them. The authors have a basis for doing so because they have been able to collect and analyze information from primary resources in archives and special collections, as well as in the course of hundreds of hours spent on interviewing scientists who operated the Soviet BW program. During his presentation, Zilinskas will discuss tentative findings that encompass subjects such as whether the application of genetic engineering, which resulted in among other accomplishments the development of multiantibiotic resistant Bacillus anthracis, Francisella tularensis, and Yersinia pestis, actually resulted in improved weaponry and whether genetically engineered strains remain in Russian cell culture collections and from there might escape or be made available to those who seek to acquire biological weapons.


About the speaker: Raymond A. Zilinskas, formerly a clinical microbiologist, is the director of the Chemical and Biological Weapons Nonproliferation Program at the Center for Nonproliferation Studies of the Monterey Institute of International Studies. He is the editor of Biological Warfare: Modern Offense and Defense (Lynne Rienner, 1999) and co-editor of the Encyclopedia of Bioterrorism Defense (Wiley, 2005). He received a PhD from the University of Southern California and a BA in Biology from the University of Stockholm.

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Raymond Zilinskas Director, Biological Weapons Nonproliferation Program Speaker Monterey Institute for International Studies
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Russia has had a long history of opposing US missile defense activities. Most recently, Russian concern focused on the alleged capability of the "third site" to intercept Russian ICBMs. The "third site" was a plan to place 10 ground-based interceptors in Poland and a large X-band radar in the Czech Republic proposed by the Bush Administration prior to its cancellation in 2009 by the Obama Administration. Now this same Russian concern has arisen regarding phases III and IV of the Phased Adaptive Approach to European missile defense proposed by the Obama Administration. This talk will assess the extent to which Russian concerns are valid in military/technical terms.


Speaker Biography:

Dean Wilkening is a Senior Research Scientist at the Center for International Security and Cooperation at Stanford University. He holds a Ph.D. in physics from Harvard University and worked at the RAND Corporation prior to coming to Stanford. His major research interests include nuclear strategy and policy, arms control, the proliferation of nuclear and biological weapons, bioterrorism, ballistic missile defense, and energy and security. His most recent research focuses on the broad strategic and political implications of ballistic missile defense deployments in Northeast Asia, South Asia and Europe. Prior work focused on the technical feasibility of boost-phase ballistic missile defense interceptors. His recent work on bioterrorism focuses on understanding the scientific and technical uncertainties associated with predicting the outcome of hypothetical airborne biological attacks and the human effects of inhalation anthrax, with the aim of devising more effective civil defenses. He has participated in, and briefed, several US National Academy of Science committees on biological terrorism and consults for several US national laboratories and government agencies.

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Dean Wilkening Senior Research Scientist Speaker CISAC
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Kathleen Vogel Assistant Professor of Peace Studies and of Science & Technology Studies Speaker Cornell University

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Shorenstein APARC Fellow
Affiliated Scholar at the Stanford Center on China's Economy and Institutions
tom_fingar_vert.jpg PhD

Thomas Fingar is a Shorenstein APARC Fellow in the Freeman Spogli Institute for International Studies at Stanford University. He was the inaugural Oksenberg-Rohlen Distinguished Fellow from 2010 through 2015 and the Payne Distinguished Lecturer at Stanford in 2009.

From 2005 through 2008, he served as the first deputy director of national intelligence for analysis and, concurrently, as chairman of the National Intelligence Council. Fingar served previously as assistant secretary of the State Department’s Bureau of Intelligence and Research (2000-01 and 2004-05), principal deputy assistant secretary (2001-03), deputy assistant secretary for analysis (1994-2000), director of the Office of Analysis for East Asia and the Pacific (1989-94), and chief of the China Division (1986-89). Between 1975 and 1986 he held a number of positions at Stanford University, including senior research associate in the Center for International Security and Arms Control.

Fingar is a graduate of Cornell University (A.B. in Government and History, 1968), and Stanford University (M.A., 1969 and Ph.D., 1977 both in political science). His most recent books are From Mandate to Blueprint: Lessons from Intelligence Reform (Stanford University Press, 2021), Reducing Uncertainty: Intelligence Analysis and National Security (Stanford University Press, 2011), The New Great Game: China and South and Central Asia in the Era of Reform, editor (Stanford University Press, 2016), Uneasy Partnerships: China and Japan, the Koreas, and Russia in the Era of Reform (Stanford, 2017), and Fateful Decisions: Choices that will Shape China’s Future, co-edited with Jean Oi (Stanford, 2020). His most recent article is, "The Role of Intelligence in Countering Illicit Nuclear-Related Procurement,” in Matthew Bunn, Martin B. Malin, William C. Potter, and Leonard S Spector, eds., Preventing Black Market Trade in Nuclear Technology (Cambridge, 2018)."

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Thomas Fingar Oksenberg/Rohlen Distinguished Fellow Speaker CISAC
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Exponential advances in the life sciences, particularly in the realm of biotechnology, have been held to raise the classic concerns of "dual-use" research: the same technologies that propel scientific advances critical to human health, the environment and economic growth also could be misused to develop biological weapons, including for bioterrorism.  However, there is significant disagreement as to whether this depiction appropriately frames the nature of the problem.  Some scientists have characterized the prevailing policy discourse on the life sciences as the "half-pipe of doom," a bipolar approach that artificially disaggregates and decontextualizes the promise and peril of advances in the life sciences.  The panel will discuss proposals to address such concerns, focusing on whether the Intergovernmental Panel on Climate Change (IPCC) offers a transferable model of scientific and policy consensus-building for issues of safety and security of biotechnology.      

Stephen J. Stedman joined CISAC in 1997 as a senior research scholar, and was named a senior fellow at FSI and CISAC and professor of political science (by courtesy) in 2002. He served as the center's acting co-director for the 2002-2003 academic year. Currently he directs the Ford Dorsey Program in International Policy Studies at Stanford and CISAC's Interschool Honors Program in International Security Studies. His current research addresses the future of international organizations and institutions, an area of study inspired by his recent work at the United Nations. In the fall of 2003 he was recruited to serve as the research director of the U.N. High-Level Panel on Threats, Challenges and Change. Upon completion of the panel's report, A More Secure World: Our Shared Responsibility, Annan asked Stedman to stay on at the U.N. as a special advisor with the rank of assistant secretary-general, to help gain worldwide support in implementing the panel's recommendations. Following the U.N. world leaders' summit in September 2005, during which more than 175 heads of state agreed upon a global security agenda developed from the panel's work, Stedman returned to CISAC. Before coming to Stanford, Stedman was an associate professor of African studies at the Johns Hopkins University School of Advanced International Studies in Washington, D.C. He has served as a consultant to the United Nations on issues of peacekeeping in civil war, light weapons proliferation and conflict in Africa, and preventive diplomacy. In 2000 Scott Sagan and he founded the CISAC Interschool Honors Program in International Security Studies. Stedman received his PhD in political science from Stanford University in 1988.

Donald Kennedy is the editor-in-chief of Science, the journal of the American Association for the Advancement of Science, and a CESP senior fellow by courtesy. His present research program entails policy on such trans-boundary environmental problems as: major land-use changes; economically-driven alterations in agricultural practice; global climate change; and the development of regulatory policies.

Kennedy has served on the faculty of Stanford University from 1960 to the present. From 1980 to 1992 he served as President of Stanford University. He was Commissioner of the US Food and Drug Administration from 1977-79. Previously at Stanford, he was as director of the Program in Human Biology from 1973-1977 and chair of the Department of Biology from 1964-1972.

Kennedy is a member of the National Academy of Sciences, the American Academy of Arts and Sciences, and the American Philosophical Society. He served on the National Commission for Public Service and the Carnegie Commission on Science, Technology and Government, and as a founding director of the Health Effects Institute. He currently serves as a director of the Carnegie Endowment for International Peace, and as co-chair of the National Academies' Project on Science, Technology and Law. Kennedy received AB and PhD degrees in biology from Harvard University.

Drew Endy is a synthetic biologist with the Stanford Department of Bioengineering. He was a junior fellow and later an assistant professor in the Department of Biological Engineering at MIT prior to coming to Stanford in September 2008 as an assistant professor in the Department of Bioengineering. Endy's research focus is on synthetic biology. With researchers at MIT he works on the engineering of standardized biological components, devices, and parts, collectively known as "BioBricks." He is one of several founders of the Registry of Standard Biological Parts, and invented an abstraction hierarchy for integrated genetic systems. Endy is known for his opposition to limited ownership and supports free access to genetic information. He has been one of the early promoters of open-source biology, and helped to start the Biobricks Foundation, a non-profit supporting open-source biology.

Tarun Chhabra is a JD candidate and Paul and Daisy Soros Fellow at Harvard Law School, and a doctoral candidate in international relations at Oxford University.  Tarun previously worked in the Executive Office of UN Secretary-General Kofi Annan, and on the staff of Annan's High-level Panel on Threats, Challenges and Change.  He also served as a consultant-advisor to the Norwegian Foreign Ministry on nuclear non-proliferation and disarmament initiatives. He was a Fulbright Scholar in Russia at the Moscow State Institute for International Relations (MGIMO) and received a Marshall Scholarship to study at Merton College, Oxford, where he earned a MPhil in international relations and was an instructor in international relations at Stanford House.  He holds a BA from Stanford University, where he worked at the Martin Luther King, Jr., Papers Project and was in the honors program at CISAC. Tarun is a Fellow of the Truman National Security Project and a member of the International Institute for Strategic Studies.

Chris Field is the founding director of the Carnegie Institution's Department of Global Ecology, Professor of Biology and Environmental Earth System Science at Stanford University, and Faculty Director of Stanford's Jasper Ridge Biological Preserve. He also is co-chair of Working Group 2 of the Intergovernmental Panel on Climate Change (IPCC) and will lead the fifth assessment report on climate change impacts, adaptation, and vulnerability.  The author of more than 200 scientific publications, Field’s research emphasizes impacts of climate change, from the molecular to the global scale. Field’s work with models includes studies on the global distribution of carbon sources and sinks, and studies on environmental consequences of expanding biomass energy. Field has served on many national and international committees related to global ecology and climate change and was a coordinating lead author for the fourth assessment report of the Intergovernmental Panel on Climate Change. Field has testified before House and Senate committees and has appeared on media from NPR “Science Friday” to BBC “Your World Today”. He is a member of the US National Academy of Sciences. Field received his PhD from Stanford in 1981 and has been at the Carnegie Institution for Science since 1984.

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Senior Fellow at the Freeman Spogli Institute for International Studies
Professor, by courtesy, of Political Science
Stedman_Steve.jpg PhD

Stephen Stedman is a Senior Fellow at the Freeman Spogli Institute for International Studies (FSI) and the Center on Democracy, Development and the Rule of Law (CDDRL), an affiliated faculty member at CISAC, and professor of political science (by courtesy) at Stanford University. He is director of CDDRL's Fisher Family Honors Program in Democracy, Development and Rule of Law, and will be faculty director of the Program on International Relations in the School of Humanities and Sciences effective Fall 2025.

In 2011-12 Professor Stedman served as the Director for the Global Commission on Elections, Democracy, and Security, a body of eminent persons tasked with developing recommendations on promoting and protecting the integrity of elections and international electoral assistance. The Commission is a joint project of the Kofi Annan Foundation and International IDEA, an intergovernmental organization that works on international democracy and electoral assistance.

In 2003-04 Professor Stedman was Research Director of the United Nations High-level Panel on Threats, Challenges and Change and was a principal drafter of the Panel’s report, A More Secure World: Our Shared Responsibility.

In 2005 he served as Assistant Secretary-General and Special Advisor to the Secretary- General of the United Nations, with responsibility for working with governments to adopt the Panel’s recommendations for strengthening collective security and for implementing changes within the United Nations Secretariat, including the creation of a Peacebuilding Support Office, a Counter Terrorism Task Force, and a Policy Committee to act as a cabinet to the Secretary-General.

His most recent book, with Bruce Jones and Carlos Pascual, is Power and Responsibility: Creating International Order in an Era of Transnational Threats (Washington DC: Brookings Institution, 2009).

Director, Fisher Family Honors Program in Democracy, Development and Rule of Law
Director, Program in International Relations
Affiliated faculty at the Center for International Security and Cooperation
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Stephen J. Stedman Professor of Political Science (by courtesy) and Senior Fellow at CISAC and FSI Speaker
Donald Kennedy President Emeritus of Stanford University; Bing Professor of Environmental Science and Policy, Emeritus and FSI Senior Fellow by courtesy Speaker
Drew Endy Assistant Professor of Bioengineering, Stanford University Speaker
Tarun Chhabra JD Candidate, Harvard Law School; DPhil, Oxford Speaker
Christopher Field Director of the Carnegie Institution's Department of Global Ecology, Professor of Biology and Environmental Earth System Science, and FSI Senior Fellow, by courtesy, Stanford University Speaker
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This talk will address alternative options for European ballistic missile defense, including the now cancelled Polish-Czech option and the recently announced Obama plan for a phased deployment of Standard Missile 3 interceptors in and around Europe. This talk will also address recent Iranian progress in developing medium-range ballistic missiles and possible missile defense cooperation with Russia.

Dean Wilkening is a Senior Research Scientist at the Center for International Security and Cooperation at Stanford University. He holds a Ph.D. in physics from Harvard University and worked at the RAND Corporation prior to coming to Stanford. His major research interests include nuclear strategy and policy, arms control, the proliferation of nuclear and biological weapons, bioterrorism, ballistic missile defense, and energy and security. His most recent research focuses on the broad strategic and political implications of ballistic missile defense deployments in Northeast Asia, South Asia and Europe. Prior work focused on the technical feasibility of boost-phase ballistic missile defense interceptors. His recent work on bioterrorism focuses on understanding the scientific and technical uncertainties associated with predicting the outcome of hypothetical airborne biological attacks and the human effects of inhalation anthrax, with the aim of devising more effective civil defenses. He has participated in, and briefed, several US National Academy of Science committees on biological terrorism and consults for several US national laboratories and government agencies.

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Dean Wilkening Senior Research Scientist, CISAC Speaker
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Abstract:  In 2003, General John Gordon, Assistant to the President for Homeland Security and former Deputy Director of the CIA asked his staff to do an end-to-end evaluation of U.S. biodefense posture.  As a result, Homeland Security Staff, directed by Dr. Kenneth Bernard, Special Assistant to the President, did a government-wide review of national preparedness and response to a bioterrorist attack.   The resulting assessment led in 2004 to the combined Homeland Security Presidential Directive #10 and National Security Presidetial Directive #17:  "Biodefense for the 21st Century."  Dr. Bernard will discuss the process and outcome of this policy that remains the U.S. national strategy for preventing and responding to a bioterrorist event. Accomplishments, outcomes and remaining gaps will be detailed, along with budget and policy implications for the next administration. 

Admiral Kenneth Bernard was appointed by President Bush to be Special Assistant to the President for Biodefense on the Homeland Security Council (HSC) in November 2002. Dr. Bernard chaired the Whitehouse Biodefense Policy Coordinating committee and drafted Decision Directives for President Bush on both "Biodefense for the 21st Century" and Agricultural Bioterrorism, and he was the White House point person on Project Bioshield - a $5.6 billion congressional bill that is speeding development and procurement of new countermeasures against biological, chemical and radiological terrorist threats.

In January 2001, Dr. Bernard was assigned by the U.S. Surgeon General to the office of Senator Bill Frist to work on international health issues of priority concern to both the Congress and the Department of Health and Human Services (HHS).   After September 11, however, he was called back to HHS to create the position of Special Adviser for National Security, Intelligence and Defense for the Department of Health and Human Services. From August 1998 to January 2001, he served on President Clinton's National Security Council (NSC) staff as Special Adviser to the Assistant to the President for National Security Affairs. Prior to joining the NSC, Dr. Bernard served as the International Health Attaché and senior representative of the U.S. Secretary of Health at the U.S. Mission to the UN in Geneva, Switzerland (1994-1998). From 1984-1989, he held positions as the Associate Director for Medical and Scientific Affairs in the Office of International Health, HHS, and as International Health Policy Adviser to the Director of the U.S. Peace Corps. He retired from the USPHS as a Rear Admiral.

He received his AB degree from the University of California, Berkeley in 1971, an M.D. from the University of California, Davis in 1975, and the DTM&H degree from the University of London School of Hygiene and Tropical Medicine in 1977.  He is a member of the Council on Foreign Relations.

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Dr. Kenneth Bernard former Special Assistant to the President for Biodefense, Homeland Security Council Speaker
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