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Biosecurity

Recent Scholarly Publications

Records 24 / 26

On Defining Global Catastrophic Biological Risks

July 2017

The Johns Hopkins Center for Health Security has formulated an encompassing working definition of global catastrophic biological risks (GCBRs) that reflects diverse sources of risk and mechanisms...

A More Systematic Approach to Biological Risk

December 2015

Management of emerging risks in life science and technology requires new leadership and a sober assessment of the legacy of Asilomar.

How likely is it that biological agents will be used deliberately to cause widespread harm?

December 2015

The fact that biological weapons have never been used—at least in recent history—is not sufficient reason to dismiss concerns that terrorists or nations could acquire and use dangerous pathogens as...

New Game, New Rules: Limiting the Risks of Biological Engineering

September 2015

In an article published by the Council on Foreign Relations' Foreign Affairs magazine, David Relman and Marc Lipsitch examine recent advances in biological engineering as well as lapses in...

Gain-of-function experiments: time for a real debate

December 2014

According to the WHO, dual use research of concern (DURC) is “life sciences research that is intended for benefit, but which might easily be misapplied to do harm”.

The Increasingly Compelling Moral Responsibilities of Life Scientists

March 2013

First paragraph of article:Many of my colleagues and fellow investigators in the life sciences were surprised in late 2011 to hear about the deliberate laboratory manipulation of highly pathogenic...

The Next Catastrophe: Reducing Our Vulnerabilities to Natural, Industrial, and Terrorist Disasters

December 2011

Charles Perrow is famous worldwide for his ideas about normal accidents, the notion that multiple and unexpected failures--catastrophes waiting to happen--are built into our society's complex...

Microbial threat lists: obstacles in the quest for biosecurity?

February 2010

Abstract: Anxiety about threats from the microbial world and about the deliberate misuse of microorganisms has led to efforts to define and control these dangers using lists and regulations.

Strategies for Combating Bioterrorism

December 2008

Modeling the Incubation Period of Inhalational Anthrax

July 2008

Ever since the pioneering work of Philip Sartwell, the incubation period distribution for infectious diseases is most often modeled using a lognormal distribution.

Analyzing the Control of Mosquito-Borne Diseases by a Dominant Lethal Genetic System

May 2007

Motivated by the failure of current methods to control dengue fever, we formulate a mathematical model to assess the impact on the spread of a mosquito-borne viral disease of a strategy that...

How Globalization Went Bad

January 2007

The article asserts that globalization has made the world a more dangerous and less orderly place.

Toward a Comprehensive Safeguards System: Keeping Fissile Materials out of Terrorists' Hands

September 2006

The nexus of terrorism and nuclear weapons is today's greatest security concern. The importance of keeping fissile materials out of the hands of terrorists is now generally accepted.

Sverdlovsk Revisited: Modeling Human Inhalation Anthrax

May 2006

Several models have been proposed for the dose-response function and the incubation period distribution for human inhalation anthrax.

Degradation of Biological Weapons Agents in the Environment: Implications for Terrorism Response

December 2005

We investigate the impact on effective terrorism response of the viability degradation of biological weapons agents in the environment.

Analyzing a Bioterror Attack on the Food Supply: The Case of Botulinum Toxin in Milk

July 2005

We developed a mathematical model of a cows-to-consumers supply chain associated with a single milk-processing facility that is the victim of a deliberate release of botulinum toxin.

An Unaddressed Issue of Agricultural Terrorism: A Case Study on Feed Security

December 2004

In the late winter of 2003, a number of livestock animals in the Midwest were poisoned due to accidental contamination of a popular commercial feed with a lethal additive.

Biotechnology and Bioterrorism: An Unprecedented World

December 2004

The web of measures that comprise the nuclear non-proliferation regime continues to hold at bay the "nuclear-armed crowd" that was part of President John F. Kennedy's alarming vision in 1963.

Effectiveness of Nuclear Weapons against Buried Biological Agents

December 2004

This report describes the results of some calculations on the effectiveness of penetrating nuclear weapons of yield 1 and 10 kilotons against targets containing biological agents.

Art or Bioterrorism? Implications of the Kurtz Case for Research Science and for Limiting Terrorist Threats

December 2004

One spring morning in 2004, Professor Steven Kurtz of the State University of New York (SUNY), Buffalo campus, woke to the horrid discovery that his wife of twenty years had died overnight from a...

Toward Biological Security

June 2002

The anthrax attacks in fall 2001, and the fear and confusion that followed, made it all too clear that the United States lacks a comprehensive strategy for coping with bioterrorism.

Keeping National Missile Defense in Perspective

January 2002

The United States is in the midst of its third major debate on nationwide ballistic missile defense-the first culminating in the 1972 ABM Treaty and the second sparked by President Reagan's "Star...

Correspondence: Responding to Chemical and Biological Threats

April 2001

The official U.S.

Biological Terrorism and Public Health

April 2001

A biological terrorist attack probably would first be detected by doctors or other health-care workers.

People

David Relman Senior Fellow Professor, Medicine, Professor, Microbiology and Immunology
Drew Endy Assistant Professor, Bioengineering
Mim John Miriam "Mim" John Affiliate